I had some free time before I got started this morning, so just for giggles, and as a test of materials, I laid out a rough 6x9 box on 11x17 10 point stock (about the weight of index card stock), threw a Frazetta Image and my logo on the front and printed it on one of the printers I have at my desk at work.
I left my guide lines (the dashed lines you can see in the photo), just so I could do some adjustments if needed to my working files. I think it came out pretty good. I had the supervisor of our pressroom bring me some heavier stock this morning, so if I get a chance this afternoon, I may make another one and see how the heavier stock does.
Photos below show the mock up of the box.